absolutely the frame rate effects damage. I get one shotted by vehicles while I am patrolling, at 1795+ power.
I can't even remember but I feel like this has been an issue for...forever. There ain' no way I'm going to play at 30fps like Tassi said he did to get past something. I'm willing to drop to 60 but that's it.
I do think that is part of the current balance issues. I agreed with what Tassi said in his video.