Are these tweaks just nonsense or anything good?

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As you probably know, there have been many security vulnerabilities discovered over the last decade, mostly affecting Intel CPUs, and especially older Intel CPUs. These vulnerabilities are often linked to performance enhancements, where Intel "cheated" in order to increase performance, and those same "cheats" were able to be exploited to create security vulnerabilities. Mitigating those vulnerabilities causes a reduction in performance as those performance-enhancing "cheats" are no longer being used.

Ideally, the mitigations that eliminate the vulnerabilities are applied via a BIOS update. This is why a newer BIOS will often perform worse than an older BIOS, particularly if you have an older Intel CPU. Anything that isn't mitigated at the BIOS level is mitigated via software at the OS level. This is what these scripts/"tweaks" do. They reverse the software/OS level mitigations, restoring performance but also opening up the vulnerabilities again.

This mainly applies to the CPUs that required the mitigations, which again mainly includes older Intel CPUs. AMD CPUs, even older AMD CPUs, were rarely affected by these issues in the first place, because AMD simply did not employ the same "cheats" that Intel did to increase performance. That's part of the reason why Intel held such a big performance lead for years after the Sandy-Bridge era. Ironically, if you go back and re-benchmark many of these older CPUs now, with the mitigations in-place, you will see that older AMD CPUs that lagged behind their similar-era Intel counterparts when they were new are now much more competitive, because the performance of the Intel CPUs has gone down (because of the mitigations) while the performance of the AMD CPUs has mostly stayed the same.

You will have to make the decision about whether it's worth it to you to sacrifice security for the benefit of a bit of extra performance. If you have a new AMD CPU, then none of this really applies to you anyway and it's probably not worth the risk of running random scripts that might end up causing other issues with your OS.

If you decide to do it anyway, at a minimum, do a bunch of benchmarks both before and afterward so you can see for yourself what difference it makes.
 
Some of them can work in various specific use cases, meaning specific hardware and application configs.
If you just want a good all purpose tweak, without worring about compatibility or security degredation, just disable the Sysmain service (Superfetch) and use an app like Shut Up 10, or WPD to disable/ block telemetry.

There are some oher minor things to do, disanling a bunch of services you might not need, but depends enitirely on your speciic use case.
 
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Just look up Chris Titus Tech debloat script and you will be good.
 
I am guessing those 'fixes' were provided by Microsoft to resolve specific scenarios and likely carry their own side effects. I wouldn't recommend just blanketing changing all those settings without understanding why it's not that way to begin with.
 
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